Nineteen of the Russian's twenty-one championships have been earned on hardcourt
A comeback Medvedev won his maiden championship for 882 days with a win over Corentin Moutet in the tournament title decider.
The athlete, a former top-ranked player, has endured a difficult season, managing just one match at the Grand Slams and experiencing a setback at the American major.
Medvedev's unpredictability on the tennis tour - and struggles with his serve in specific - resulted in him falling of the elite rankings and ultimately separating with long-time mentor Gilles Cervara.
Now working with Thomas Johansson and Goetzke, Medvedev has consistently advanced in the past month - peaking in a closely contested three-set win over opponent Corentin Moutet.
It is Medvedev's initial title since the Rome competition and maiden on a hardcourt after spring of that year.
Victory also means he has won twenty-one titles at 21 different tournaments.
"This marks the first occasion I am participating in a competition with my both daughters together, so to secure a title is especially meaningful," stated world number 14 the champion.
"This title is in tribute of my second daughter her name, because the maiden victory I won when my older daughter my daughter was delivered was for her."
Medvedev, the past champion, had lost his previous six finals, including in the German tournament in the past months.
His counter-punching strategy and frequent emotional displays on the playing surface had led commentators to wonder if his skill to compete at the highest level was finished.
But the player has altered his approach in recent weeks, making an effort to approach the net and perform aggressively, supported by an improved serving game.
Medvedev fought back from a break down in the initial set against the tricky Frenchman, winning four of the last five exchanges to take the lead.
The competitors traded break points in the middle set before Moutet, striving for his initial tour title, took control to create a decider.
He defended 4 initial chances in a competitive third set before the champion broke to 15 to secure the win.
Appropriately, the winner clinched the title with a point at the net, with the Frenchman incapable to control a shot after over two and a half hours.